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[波兰及全球评估职业性接触结晶硅尘的背景]

[Backgrounds for assessing occupational exposure to crystalline silica dust in Poland and worldwide].

作者信息

Maciejewska Aleksandra

机构信息

Zakład Srodowiskowych Zagrozeń Zdrowia, Instytut Medycyny Pracy im. prof. J. Nofera, Łódź.

出版信息

Med Pr. 2007;58(4):327-44.

Abstract

Crystalline silica is an agent harmful to human health, and quite frequently present in occupational environments. Occupational groups exposed to crystalline silica dust include mostly workers of the mineral and coal mining as well as metallurgical, chemical and construction industries. In the European Union (EU), the number of those exposed to this agent is estimated at over 2 million persons. In Poland, the number of people employed under conditions of excessive silica dust exposure exceeds 50 thousand. The assessment of occupational exposure to crystalline silica comprises several steps: primarily workplace determinations, quantitative sample analyses and comparisons of the obtained results with admissible values. This work describes a set of instruments that enables direct comparison of the study results with admissible values binding in almost 40 countries. It also highlights the consequences resulting from the classification of quartz and cristobalite, the most common forms of crystalline silica, as carcinogens by the International Agency for Research on Cancer (IARC). A survey of air sampling and dust determination methods used in various countries to measure airborne dust concentrations of crystalline silica in occupational environments are presented along with relevant tables. The GESTIS data base, specifying the methods considered by EU as suitable for measuring and assessing harmful agents, was used as the selection criterion. Particular attention was paid to the methods used to determine crystalline silica; the effect of analytical methods applied, sample preparation procedures, and reference materials on the results of determinations was also analyzed. Main parameters of method validation, such as detection and determination limits, and precision of the analysis were compared.

摘要

结晶二氧化硅是一种对人体健康有害的物质,在职业环境中相当常见。接触结晶二氧化硅粉尘的职业群体主要包括采矿、煤炭开采以及冶金、化工和建筑行业的工人。在欧盟(EU),估计接触这种物质的人数超过200万。在波兰,在二氧化硅粉尘过度暴露条件下工作的人数超过5万。对职业性接触结晶二氧化硅的评估包括几个步骤:主要是工作场所测定、定量样品分析以及将所得结果与允许值进行比较。这项工作描述了一套仪器,可直接将研究结果与近40个国家具有约束力的允许值进行比较。它还强调了国际癌症研究机构(IARC)将石英和方石英(结晶二氧化硅最常见的形式)归类为致癌物所产生的后果。文中还列出相关表格,对各国用于测量职业环境中结晶二氧化硅空气传播粉尘浓度的空气采样和粉尘测定方法进行了调查。以GESTIS数据库作为选择标准,该数据库规定了欧盟认为适合测量和评估有害物质的方法。特别关注了用于测定结晶二氧化硅的方法;还分析了所应用的分析方法、样品制备程序和参考材料对测定结果的影响。比较了方法验证的主要参数,如检测限、测定限和分析精密度。

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