Giuliano François, Amar Edouard, Chevallier Daniel, Montaigne Olivier, Joubert Jean-Michel, Chartier-Kastler Emmanuel
AP-HP, Raymond Poincaré Hospital, Garches, France.
J Sex Med. 2008 Feb;5(2):448-57. doi: 10.1111/j.1743-6109.2007.00670.x. Epub 2007 Nov 27.
There is little sound information on how urologists manage erectile dysfunction (ED) arising after radical prostatectomy (RP) in a real-world situation.
To perform a national survey of how French urologists manage ED after RP in routine practice.
Choice of first-line treatment, type of treatment (rehabilitation of erectile function vs. treatment on demand for intercourse), and timing and duration of treatment.
All French urologists were invited to take part in a survey; 59.7% accepted provisionally (760/1,272). They received the survey questionnaire and 10 patient data forms to be completed during the visits of the first 10 patients with fewer than 12 months follow-up post-RP. These were returned to an independent third party for analysis.
The final response rate was 535/1,272 (42%). Before performing RP, 80% of the urologists assessed sexual activity and 76% erectile function; 9% did neither. Thirty-eight percent reported that they systematically proposed ED treatment to their patients post-RP ("routine prescribers"). The remainder was treated on occasion, either at the patients' request (49%) or at their own discretion (13%). Routine prescribers tended to be younger and had performed more RPs in the preceding year. Most urologists (88%) always used the same first-line treatment: regular intracavernosal injections (ICIs) for rehabilitation, 39%; ICI on demand for intercourse, 30%; phosphodiesterase type 5 (PDE5) inhibitors on demand, 16%, or regular PDE5 inhibitors for rehabilitation, 8%; alternating ICI and PDE5 inhibitors, 7%; vacuum device, <1%. ED treatment was initiated within 3 months of RP by 72% of the urologists (92% of routine prescribers). The percentage of urologists recommending ED treatment for 6 months was 20%, 38% for 1 year, and 33% for 2 years.
ED was commonplace after RP. French urologists reported a proactive attitude to ED treatment, many favoring pharmacologic rehabilitation therapy. ICI was their first-line treatment of choice.
在现实临床中,关于泌尿外科医生如何处理根治性前列腺切除术后(RP)出现的勃起功能障碍(ED),几乎没有可靠的信息。
对法国泌尿外科医生在日常临床实践中如何处理RP术后ED进行全国性调查。
一线治疗的选择、治疗类型(勃起功能康复治疗与按需进行性交治疗)以及治疗的时机和持续时间。
邀请所有法国泌尿外科医生参与一项调查;59.7%的医生初步接受邀请(760/1272)。他们收到调查问卷以及10份患者数据表格,要求在RP术后随访时间少于12个月的前10例患者就诊期间填写。这些问卷和表格随后被返还给一个独立的第三方进行分析。
最终回复率为535/1272(42%)。在进行RP之前,80%的泌尿外科医生评估患者的性活动情况,76%评估勃起功能;9%两者均未评估。38%的医生报告说他们在RP术后会系统地向患者推荐ED治疗(“常规处方医生”)。其余患者则根据情况进行治疗,要么是应患者要求(49%),要么是由医生自行决定(13%)。常规处方医生往往较为年轻,且在前一年进行的RP手术更多。大多数泌尿外科医生(88%)总是采用相同的一线治疗方法:定期海绵体内注射(ICI)进行康复治疗,占39%;按需进行ICI用于性交,占30%;按需使用5型磷酸二酯酶(PDE5)抑制剂,占16%,或定期使用PDE5抑制剂进行康复治疗,占8%;交替使用ICI和PDE5抑制剂,占7%;使用真空装置的比例不到1%。72%的泌尿外科医生在RP术后3个月内开始进行ED治疗(92%的常规处方医生)。建议进行ED治疗6个月的泌尿外科医生比例为20%,1年的为38%,2年的为33%。
RP术后ED很常见。法国泌尿外科医生报告了对ED治疗的积极态度,许多人倾向于药物康复治疗。ICI是他们首选的一线治疗方法。