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法国泌尿外科学会关于根治性前列腺切除术后泌尿外科医生如何处理勃起功能障碍的全国性调查(REPAIR)

How urologists manage erectile dysfunction after radical prostatectomy: a national survey (REPAIR) by the French urological association.

作者信息

Giuliano François, Amar Edouard, Chevallier Daniel, Montaigne Olivier, Joubert Jean-Michel, Chartier-Kastler Emmanuel

机构信息

AP-HP, Raymond Poincaré Hospital, Garches, France.

出版信息

J Sex Med. 2008 Feb;5(2):448-57. doi: 10.1111/j.1743-6109.2007.00670.x. Epub 2007 Nov 27.

Abstract

INTRODUCTION

There is little sound information on how urologists manage erectile dysfunction (ED) arising after radical prostatectomy (RP) in a real-world situation.

AIM

To perform a national survey of how French urologists manage ED after RP in routine practice.

MAIN OUTCOME MEASURES

Choice of first-line treatment, type of treatment (rehabilitation of erectile function vs. treatment on demand for intercourse), and timing and duration of treatment.

METHODS

All French urologists were invited to take part in a survey; 59.7% accepted provisionally (760/1,272). They received the survey questionnaire and 10 patient data forms to be completed during the visits of the first 10 patients with fewer than 12 months follow-up post-RP. These were returned to an independent third party for analysis.

RESULTS

The final response rate was 535/1,272 (42%). Before performing RP, 80% of the urologists assessed sexual activity and 76% erectile function; 9% did neither. Thirty-eight percent reported that they systematically proposed ED treatment to their patients post-RP ("routine prescribers"). The remainder was treated on occasion, either at the patients' request (49%) or at their own discretion (13%). Routine prescribers tended to be younger and had performed more RPs in the preceding year. Most urologists (88%) always used the same first-line treatment: regular intracavernosal injections (ICIs) for rehabilitation, 39%; ICI on demand for intercourse, 30%; phosphodiesterase type 5 (PDE5) inhibitors on demand, 16%, or regular PDE5 inhibitors for rehabilitation, 8%; alternating ICI and PDE5 inhibitors, 7%; vacuum device, <1%. ED treatment was initiated within 3 months of RP by 72% of the urologists (92% of routine prescribers). The percentage of urologists recommending ED treatment for 6 months was 20%, 38% for 1 year, and 33% for 2 years.

CONCLUSION

ED was commonplace after RP. French urologists reported a proactive attitude to ED treatment, many favoring pharmacologic rehabilitation therapy. ICI was their first-line treatment of choice.

摘要

引言

在现实临床中,关于泌尿外科医生如何处理根治性前列腺切除术后(RP)出现的勃起功能障碍(ED),几乎没有可靠的信息。

目的

对法国泌尿外科医生在日常临床实践中如何处理RP术后ED进行全国性调查。

主要观察指标

一线治疗的选择、治疗类型(勃起功能康复治疗与按需进行性交治疗)以及治疗的时机和持续时间。

方法

邀请所有法国泌尿外科医生参与一项调查;59.7%的医生初步接受邀请(760/1272)。他们收到调查问卷以及10份患者数据表格,要求在RP术后随访时间少于12个月的前10例患者就诊期间填写。这些问卷和表格随后被返还给一个独立的第三方进行分析。

结果

最终回复率为535/1272(42%)。在进行RP之前,80%的泌尿外科医生评估患者的性活动情况,76%评估勃起功能;9%两者均未评估。38%的医生报告说他们在RP术后会系统地向患者推荐ED治疗(“常规处方医生”)。其余患者则根据情况进行治疗,要么是应患者要求(49%),要么是由医生自行决定(13%)。常规处方医生往往较为年轻,且在前一年进行的RP手术更多。大多数泌尿外科医生(88%)总是采用相同的一线治疗方法:定期海绵体内注射(ICI)进行康复治疗,占39%;按需进行ICI用于性交,占30%;按需使用5型磷酸二酯酶(PDE5)抑制剂,占16%,或定期使用PDE5抑制剂进行康复治疗,占8%;交替使用ICI和PDE5抑制剂,占7%;使用真空装置的比例不到1%。72%的泌尿外科医生在RP术后3个月内开始进行ED治疗(92%的常规处方医生)。建议进行ED治疗6个月的泌尿外科医生比例为20%,1年的为38%,2年的为33%。

结论

RP术后ED很常见。法国泌尿外科医生报告了对ED治疗的积极态度,许多人倾向于药物康复治疗。ICI是他们首选的一线治疗方法。

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