Lima T J, Ribeiro C C C, Tenuta L M A, Cury J A
Faculty of Dentistry, Federal University of Maranhão, UFMA, São Luís, Brazil.
Caries Res. 2008;42(1):46-50. doi: 10.1159/000111749. Epub 2007 Nov 27.
Since there is no consensus on the anticaries effectiveness of low-fluoride (F) dentifrice, this randomized clinical trial evaluated its effect in children at different caries activity status. One hundred and twenty 2- to 4-year-old children, half with and half without active caries lesions, were randomly divided into 2 groups which used 500- or 1,100-microg F/g (NaF) dentifrices during 1 year. Caries progression or regression were evaluated as the number of lesions becoming active/cavities or inactive, respectively. The anticaries effect of the low-F dentifrice was similar to the conventional F dentifrice when used by caries-inactive children. However, in children with active caries lesions the low-F dentifrice was less effective than the 1,100-microg F/g dentifrice in controlling the progression of lesions. The data suggest that the child caries activity may be taken into account to recommend a low-F dentifrice.
由于对于低氟牙膏的防龋效果尚无共识，这项随机临床试验评估了其对处于不同龋病活动状态儿童的效果。120名2至4岁儿童，其中一半有活动性龋损，一半没有，被随机分为两组，在1年时间里分别使用含氟量为500或1100微克/克（氟化钠）的牙膏。龋病进展或逆转分别根据病变变为活动性/龋洞或变为非活动性的数量来评估。当无龋儿童使用低氟牙膏时，其防龋效果与传统含氟牙膏相似。然而，对于有活动性龋损的儿童，低氟牙膏在控制病变进展方面不如含氟量为1100微克/克的牙膏有效。数据表明，在推荐低氟牙膏时可能需要考虑儿童的龋病活动情况。
