Xie Lixin, Gao Hua, Shi Weiyun
State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.
Cornea. 2007 Dec;26(10):1200-4. doi: 10.1097/ICO.0b013e31815654a5.
To determine the long-term safety and effectiveness of photorefractive keratectomy (PRK) in the treatment of refractive errors after epikeratophakia (EP) for keratoconus.
Ten patients (14 eyes) who had refractive errors after EP for keratoconus received PRK surgery. Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), refractive error, corneal astigmatism, pachymetry, corneal topography, and complications were monitored.
Mean follow-up after PRK was 63.4 +/- 19.8 months. Mean spherical equivalent was -5.5 +/- 3.9 D before PRK, -0.9 +/- 0.5 D at 1 month after PRK, and -1.5 +/- 1.0 D at 3 years. Mean astigmatism was 4.2 +/- 2.1 D before PRK, 1.2 +/- 0.5 D at 1 month after PRK, and 1.5 +/- 0.6 D at 3 years. Thirteen (93%) eyes had an UCVA <20/40, and 12 (86%) had a BSCVA of 20/40 or better before PRK. At 1 year, the UCVA was 20/40 or better in 8 (57%) eyes, and the BSCVA was 20/40 or better in all eyes. Mean central corneal thickness was 749 +/- 35 microm before PRK and 621 +/- 56 mum at 3 years. During the follow-up period, haze (grade no more than 1.0) was observed in 2 eyes. No immune rejection episode or recurrent keratoconus was found.
PRK appears to be reliable and safe for the correction of residual ametropia after EP for keratoconus, and the visual acuity can remain stable after PRK for a long time.
确定准分子激光角膜切削术(PRK)治疗圆锥角膜表面镜片术(EP)后屈光不正的长期安全性和有效性。
10例(14只眼)圆锥角膜EP术后出现屈光不正的患者接受了PRK手术。监测裸眼视力(UCVA)、最佳矫正视力(BSCVA)、屈光不正、角膜散光、角膜厚度测量、角膜地形图及并发症。
PRK术后平均随访时间为63.4±19.8个月。PRK术前平均等效球镜度为-5.5±3.9D,术后1个月为-0.9±0.5D,3年时为-1.5±1.0D。PRK术前平均散光为4.2±2.1D,术后1个月为1.2±0.5D,3年时为1.5±0.6D。13只眼(93%)PRK术前UCVA<20/40,12只眼(86%)BSCVA为20/40或更好。1年时,8只眼(57%)UCVA为20/40或更好,所有眼BSCVA均为20/40或更好。PRK术前平均中央角膜厚度为749±35μm,3年时为621±56μm。随访期间,2只眼观察到 haze(等级不超过1.0)。未发现免疫排斥反应或圆锥角膜复发。
PRK对于圆锥角膜EP术后残余屈光不正的矫正似乎可靠且安全,且PRK术后视力可长期保持稳定。