Vestergaard Hanne, Wohlfahrt Jan, Westergaard Tine, Pipper Christian, Rasmussen Niels, Melbye Mads
Department of Epidemiology Research, Statens Serum Institut, Copenhagen S, Denmark.
Pediatr Infect Dis J. 2007 Dec;26(12):1117-21. doi: 10.1097/INF.0b013e31814536ba.
Tonsillectomy is one of the most frequent operations performed on children and young adults, but little is known regarding its distribution by age, sex, and calendar period.
We designed a population-based cohort study including all Danish residents from 1980 to 2001 to describe national incidence figures for tonsillectomy. Persons undergoing tonsillectomy were identified in the Danish National Patient Registry and from the Danish Health Security System. Overall, the cohort consisted of 6.3 million persons, who were followed up for 106.9 million person-years.
During the study period 153,212 patients had tonsillectomies, comprising 84,831 females and 68,381 males. The age-specific incidence of tonsillectomy peaked at 4 years of age for both boys and girls, with 9.7 and 6.9 tonsillectomies per 1000 person-years, respectively. A second peak emerged during teenage years in both sexes, being highest among girls with 8.6 tonsillectomies per 1000 person-years at 16 years of age and 3.1 tonsillectomies per 1000 person-years among 17-year-old boys. The cumulative risk of tonsillectomy during the first 20 years of life increased from 7.9% among females and 6.0% among males in 1980 to 9.2% and 7.7%, respectively, in 2001. Over 90% of the patients less than 20 years of age registered at hospital with chronic disease of the tonsils had tonsillectomies within a year.
The incidence of tonsillectomy revealed significant gender differences. Furthermore, 2 incidence peaks emerged at age 4 years and age 16-17 years. The second peak in adolescence was particularly pronounced for females and is unexplained.
扁桃体切除术是儿童和年轻人中最常见的手术之一，但对于其按年龄、性别和日历时间段的分布情况却知之甚少。
我们设计了一项基于人群的队列研究，纳入了1980年至2001年期间所有丹麦居民，以描述全国扁桃体切除术的发病率数据。在丹麦国家患者登记处和丹麦健康保障系统中识别出接受扁桃体切除术的患者。总体而言，该队列由630万人组成，随访了1.069亿人年。
在研究期间，153,212例患者接受了扁桃体切除术，其中女性84,831例，男性68,381例。扁桃体切除术的年龄特异性发病率在4岁时达到峰值，男孩和女孩每1000人年分别为9.7例和6.9例。第二个峰值出现在青少年时期，在女孩中最为明显，16岁时每1000人年有8.6例，17岁男孩中每1000人年有3.1例。在生命的前20年中，扁桃体切除术的累积风险从1980年女性的7.9%和男性的6.0%分别增加到2001年的9.2%和7.7%。90%以上因扁桃体慢性病在医院登记的20岁以下患者在一年内接受了扁桃体切除术。
扁桃体切除术的发病率显示出显著的性别差异。此外，在4岁和16 - 17岁出现了两个发病高峰。青春期的第二个高峰在女性中尤为明显，原因不明。
