Vianello A, Costantini E, Del Zingaro M, Porena M
Section of Urology and Andrology, Department of Medical-Surgical Specialties and Public Health, University of Perugia, Santa Maria della Misericordia Hospital, Perugia, Italy.
Minerva Ginecol. 2007 Dec;59(6):557-69.
The aim of this study was to review recent literature on mini-invasive surgical technique for the treatment of female stress urinary incontinence (SUI). Surgical aspects, intraoperative and perioperative complications and objective and subjective outcomes were analyzed and compared.
The PubMed databank from 2000 to February 2007 was searched for original prospective and randomized studies in English, on surgical treatment of female SUI, which avoided a laparotomic access to the female pelvis. Studies had to investigate at least 40 women with a minimum follow-up of 12 months.
A total of 38 prospective studies were found: 27 of them were on mid-urethral slings; 8 assessed urethral injections; and 3 radiofrequency treatment. Fifteen studies were randomized. Follow-ups ranged from 12 to 60 months, except for sexual function which had a 6-month follow-up. Ten out of 38 studies assessed patients who did not refer pelvic organ prolapse or detrusor overactivity and had not undergone any previous anti-incontinence procedure.
Mid-urethral slings showed good outcomes and are safe and brief to perform and have a relatively short learning curve. Urethral injections showed discouraging results, as they have poor outcomes and repetitive treatments are frequently necessary. Injections can be used in women with contraindications to major surgical procedures, with intrinsic sphincter deficiency as the main cause of incontinence. Radiofrequency showed worse results than mid-urethral slings and is a valuable choice in women who refuse more invasive procedures. The development of studies with longer follow-ups on mini-invasive surgical techniques are encouraged.
本研究旨在综述近期关于治疗女性压力性尿失禁(SUI)的微创外科技术的文献。分析并比较手术方面、术中及围手术期并发症以及客观和主观结果。
检索2000年至2007年2月的PubMed数据库,查找英文的关于女性SUI手术治疗的原始前瞻性和随机研究,这些研究避免通过剖腹手术进入女性骨盆。研究必须纳入至少40名女性,且随访时间至少为12个月。
共找到38项前瞻性研究:其中27项是关于中段尿道吊带术;8项评估了尿道注射;3项是射频治疗。15项研究为随机研究。随访时间从12个月至60个月不等,性功能随访时间为6个月。38项研究中有10项评估了未提及盆腔器官脱垂或逼尿肌过度活动且之前未接受过任何抗尿失禁手术的患者。
中段尿道吊带术显示出良好的效果,操作安全、简便,学习曲线相对较短。尿道注射的结果令人沮丧,因为其效果不佳且常常需要重复治疗。注射可用于有重大手术禁忌证、以内在括约肌缺陷为主要尿失禁原因的女性。射频治疗的结果比中段尿道吊带术差,是拒绝接受更具侵入性手术的女性的一个有价值的选择。鼓励开展对微创外科技术进行更长时间随访的研究。