[帕尔米定在肝脏毒性损伤中的抗氧化特性]
[The antioxidant properties of parmidine in a toxic lesion of the liver].
作者信息
Riabkov A N, Uzbekova D G, Artem'eva G B, Nikulin A A
出版信息
Farmakol Toksikol. 1991 Nov-Dec;54(6):35-7.
PMID:1804692
Abstract
The experiments on rats with toxic lesions of the liver induced by tetrachlorinemethane showed that parmidine (pyridinolcarbamat) promotes the reduction of the activity of lipid peroxidation in the liver tissue homogenates and erythrocytes. The pronounced tendency towards normalization of free-radical oxidation correlated with the positive dynamics of the histological picture of the liver.
摘要
用四氯化碳诱导大鼠产生肝中毒性损伤的实验表明，巴马汀（吡啶醇氨基甲酸酯）可促进肝组织匀浆和红细胞中脂质过氧化活性的降低。自由基氧化明显趋于正常化的趋势与肝脏组织学图像的积极动态变化相关。
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