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提高老年人阿司匹林的胃肠道耐受性。

Improving the gastrointestinal tolerability of aspirin in older people.

作者信息

Newton Julia L

机构信息

Institute for Ageing and Health, University of Newcastle upon Tyne, Care of the Elderly Offices, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

出版信息

Clin Interv Aging. 2006;1(1):33-9. doi: 10.2147/ciia.2006.1.1.33.

DOI:10.2147/ciia.2006.1.1.33
PMID:18047255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2682452/
Abstract

Interventions to reduce mortality and disability in older people are vital. Aspirin is cheap and effective and known to prevent cardiovascular and cerebrovascular disease, many cancers, and Alzheimer dementia. The widespread use of aspirin in older people is limited by its gastrointestinal side effects. Understanding age-related changes in gastrointestinal physiology that could put older people at risk of the side effects of aspirin may direct strategies to improve tolerance and hence lead to greater numbers of older people being able to take this effective intervention.

摘要

降低老年人死亡率和残疾率的干预措施至关重要。阿司匹林价格低廉且效果显著，已知其可预防心血管和脑血管疾病、多种癌症以及阿尔茨海默病性痴呆。阿司匹林在老年人中的广泛应用受到其胃肠道副作用的限制。了解与年龄相关的胃肠道生理变化，这些变化可能使老年人面临阿司匹林副作用的风险，或许能指导改善耐受性的策略，从而使更多老年人能够接受这种有效的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6809/2682452/3b0a605d9197/cia0101-033-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6809/2682452/9ad230e5eec2/cia0101-033-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6809/2682452/3b0a605d9197/cia0101-033-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6809/2682452/9ad230e5eec2/cia0101-033-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6809/2682452/3b0a605d9197/cia0101-033-f2.jpg

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