Levisohn Paul M
University of Colorado at Denver, Denver, CO 80218, USA.
Epilepsia. 2007;48 Suppl 9:33-5. doi: 10.1111/j.1528-1167.2007.01399.x.
The high prevalence of epilepsy in children with autism supports a neurobiologic etiology for autism. It remains unclear whether seizures and epileptiform activity on the EEG are causative or comorbid. It is also uncertain if focal epileptiform EEG abnormalities may be associated with stable cognitive impairment. Even less clear is whether these EEG abnormalities can result in the combination of language and social dysfunction seen in autistic spectrum disorders.
自闭症儿童中癫痫的高患病率支持自闭症的神经生物学病因。脑电图上的癫痫发作和癫痫样活动是病因性的还是共病性的仍不清楚。局灶性癫痫样脑电图异常是否可能与稳定的认知障碍相关也不确定。更不清楚的是,这些脑电图异常是否会导致自闭症谱系障碍中出现的语言和社交功能障碍的合并情况。