Miwa Keisuke, Araki Yasumi, Ishibashi Nobuya, Shirouzu Kazuo
Department of Surgery, Kurume University School of Medicine, Fukuoka, Japan.
Int Surg. 2007 Jul-Aug;92(4):192-4.
We aimed to compare conventional single-layer mesh and composite mesh in terms of the degree of tissue repair on the abdominal wall side of the mesh and the degree of mechanical adhesion to the intestine and to confirm the stability of composite mesh. We used a single-layer polypropylene (PP) mesh and a two-layer Composix mesh (E/X type) consisting of a PP mesh and an expanded polytetrafluoroethylene mesh. Twenty rats were divided into two groups. Three months after mesh placement, histopathologically, ingrowth of granulation tissue into the mesh on the abdominal wall side was prominent without mesh shrinkage or shift in either group. In the PP mesh group, 50% of the rats had firm adhesions between the mesh and the intestine, whereas the Composix mesh group had no adhesions to the intestine. Unlike conventional PP mesh, Composix mesh prevented adhesions to the intestine on the peritoneal side without impairing tissue union with the visceral peritoneum, suggesting its usefulness in clinical onlay mesh repair for ventral defects.
我们旨在比较传统单层网片和复合网片在网片腹壁侧的组织修复程度以及与肠道的机械粘连程度，并确认复合网片的稳定性。我们使用了单层聚丙烯（PP）网片和由PP网片与膨体聚四氟乙烯网片组成的双层Composix网片（E/X型）。将20只大鼠分为两组。放置网片三个月后，组织病理学检查显示，两组腹壁侧网片内均有明显的肉芽组织长入，且无网片收缩或移位。在PP网片组中，50%的大鼠网片与肠道之间存在牢固粘连，而Composix网片组与肠道无粘连。与传统PP网片不同，Composix网片可防止腹膜侧与肠道粘连，同时不影响与脏腹膜的组织愈合，表明其在临床腹侧缺损补片修补术中具有应用价值。
