1,8-萘二甲酸酐解毒剂增强了克菌丹和福美双杀菌剂对巴西固氮螺菌细胞的毒性作用。

1,8-Naphthalic anhydride antidote enhances the toxic effects of captan and thiram fungicides on Azospirillum brasilense cells.

作者信息

Gallori E, Casalone E, Colella C M, Daly S, Polsinelli M

机构信息

Dipartimento di Biologia Animale e Genetica, University of Florence, Firenze, Italy.

出版信息

Res Microbiol. 1991 Nov-Dec;142(9):1005-12. doi: 10.1016/0923-2508(91)90011-x.

DOI:10.1016/0923-2508(91)90011-x

PMID:1805302

Abstract

The effects of ten fungicides, six herbicides and four insecticides on the nitrogen-fixing bacterium Azospirillum brasilense were examined. The fungicides captan and thiram were the most toxic among the compounds tested. Cell growth and nitrogenase activity of the bacterium were markedly inhibited by low concentrations of the two fungicides. Antidote 1,8-naphthalic anhydride increased by a factor of 2 the cellular level of glutathione. The addition of the antidote in the presence of captan or thiram caused a similar increase in the glutathione content, but at the same time enhanced the toxicity of the two fungicides.

摘要

研究了10种杀菌剂、6种除草剂和4种杀虫剂对固氮细菌巴西固氮螺菌的影响。在所测试的化合物中，杀菌剂克菌丹和福美双毒性最强。低浓度的这两种杀菌剂能显著抑制该细菌的细胞生长和固氮酶活性。解毒剂1,8 - 萘二甲酸酐使谷胱甘肽的细胞水平提高了2倍。在存在克菌丹或福美双的情况下添加解毒剂，谷胱甘肽含量有类似增加，但同时增强了这两种杀菌剂的毒性。