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Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis.
Gastroenterology. 2008 Jan;134(1):120-30. doi: 10.1053/j.gastro.2007.10.023. Epub 2007 Oct 17.
5
Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras.
Oncogene. 2004 Apr 22;23(19):3404-13. doi: 10.1038/sj.onc.1207397.
7
Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells.
J Biol Chem. 2007 May 11;282(19):14048-55. doi: 10.1074/jbc.M611089200. Epub 2007 Mar 12.
8
Inducible intestine-specific deletion of Krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon.
Dev Biol. 2014 Mar 15;387(2):191-202. doi: 10.1016/j.ydbio.2014.01.002. Epub 2014 Jan 15.
10
Krüpple-like factor 5 is required for proper maintenance of adult intestinal crypt cellular proliferation.
Dig Dis Sci. 2015 Jan;60(1):86-100. doi: 10.1007/s10620-014-3307-z. Epub 2014 Jul 29.

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KLF5 Shapes Developing Respiratory Tubules by Inhibiting Actin Asymmetry in Epithelial Cells.
Am J Respir Cell Mol Biol. 2025 Jun;72(6):663-677. doi: 10.1165/rcmb.2024-0140OC.
2
Discovery of therapeutic targets in cancer using chromatin accessibility and transcriptomic data.
Cell Syst. 2024 Sep 18;15(9):824-837.e6. doi: 10.1016/j.cels.2024.08.004. Epub 2024 Sep 4.
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Krüppel-like Factor 5 Plays an Important Role in the Pathogenesis of Chronic Pancreatitis.
Cancers (Basel). 2023 Nov 15;15(22):5427. doi: 10.3390/cancers15225427.
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New insights into KLFs and SOXs in cancer pathogenesis, stemness, and therapy.
Semin Cancer Biol. 2023 May;90:29-44. doi: 10.1016/j.semcancer.2023.02.003. Epub 2023 Feb 15.
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Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci.
Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2120633119. doi: 10.1073/pnas.2120633119. Epub 2022 May 23.
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Identifying Diagnostic MicroRNAs and Investigating Their Biological Implications in Rectal Cancer.
JAMA Netw Open. 2021 Dec 1;4(12):e2136913. doi: 10.1001/jamanetworkopen.2021.36913.
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Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer.
Nat Commun. 2021 Nov 4;12(1):6377. doi: 10.1038/s41467-021-26612-1.
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Genome-wide association study of colorectal polyps identified highly overlapping polygenic architecture with colorectal cancer.
J Hum Genet. 2022 Mar;67(3):149-156. doi: 10.1038/s10038-021-00980-4. Epub 2021 Oct 21.
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Krüppel-like factor (KLF)5: An emerging foe of cardiovascular health.
J Mol Cell Cardiol. 2022 Feb;163:56-66. doi: 10.1016/j.yjmcc.2021.10.002. Epub 2021 Oct 13.

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2
Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo.
Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14122-7. doi: 10.1073/pnas.0604130103. Epub 2006 Sep 7.
3
Physiological analysis of oncogenic K-ras.
Methods Enzymol. 2006;407:676-90. doi: 10.1016/S0076-6879(05)07053-9.
8
Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation.
Cell Res. 2005 Feb;15(2):92-6. doi: 10.1038/sj.cr.7290271.

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