Riou Emilie M, Amlie-Lefond Catherine, Echenne Bernard, Farmer Marie, Sébire Guillaume
Division of Pediatric Neurology, Montreal Children's Hospital-McGill University Health Center, Montreal, Quebec, Canada.
Pediatr Neurol. 2008 Jan;38(1):1-9. doi: 10.1016/j.pediatrneurol.2007.09.005.
With the advent of magnetic resonance imaging as a rapid and accurate way to diagnose arterial ischemic stroke, cerebrospinal fluid assessment is rarely performed, unless infectious or inflammatory processes are obvious. Recent advances in the understanding of the pathophysiology of childhood stroke have implicated a growing list of discrete or occult infectious and inflammatory conditions which may involve intracranial arteries and neighboring structures. Cerebrospinal-fluid assessment may allow the detection of markers identifying processes (including infectious, inflammatory, metabolic, and traumatic) potentially involved in cerebral vasculopathy and stroke. The analysis of cerebrospinal fluid in arterial ischemic strokes, including apparently idiopathic strokes, may yield essential information on pathophysiology, allowing for optimal therapeutic decisions and prognostic considerations.
随着磁共振成像作为诊断动脉缺血性中风的快速且准确的方法出现，除非感染或炎症过程明显，否则很少进行脑脊液评估。对儿童中风病理生理学理解的最新进展表明，越来越多的离散或隐匿性感染和炎症性疾病可能累及颅内动脉和邻近结构。脑脊液评估可能有助于检测识别可能与脑血管病变和中风有关的过程（包括感染、炎症、代谢和创伤性）的标志物。对动脉缺血性中风（包括明显特发性中风）的脑脊液分析可能会得出有关病理生理学的重要信息，从而有助于做出最佳治疗决策和进行预后考量。
