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系统性红斑狼疮相关脑缺血中显著的脑脊液细胞增多症

Marked cerebrospinal fluid pleocytosis in systemic lupus erythematosus related cerebral ischemia.

作者信息

Abialmouna J, Shoemaker D W, Pullicino P M, Baer A N

机构信息

Department of Medicine, Erie County Medical Center, Buffalo, NY.

出版信息

J Rheumatol. 1992 Apr;19(4):626-9.

PMID:1593587
Abstract

Pleocytosis of the cerebrospinal fluid (CSF) may accompany central nervous system lesions that occur as a result of systemic lupus erythematosus (SLE); however, the number of CSF white blood cells is usually less than 50/mm3 and the predominant cell is the lymphocyte. A young woman with SLE had 2 acute episodes of hemorrhagic cerebral ischemia, each of which was associated with a neutrophilic CSF pleocytosis (white blood count 480-2250/mm3). This type of meningeal reaction may have been related to the proximity of the cerebral lesions to the ventricles, a phenomenon previously described in non SLE related cerebral infarcts.

摘要

脑脊液(CSF)细胞增多可能伴随系统性红斑狼疮(SLE)所致的中枢神经系统病变;然而,脑脊液白细胞数量通常少于50/mm³,且主要细胞为淋巴细胞。一名患有SLE的年轻女性发生了2次急性出血性脑缺血发作,每次发作均伴有中性粒细胞性脑脊液细胞增多(白细胞计数480 - 2250/mm³)。这种脑膜反应类型可能与脑部病变靠近脑室有关,这一现象先前在非SLE相关的脑梗死中已有描述。

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Insights into the role of neutrophils in neuropsychiatric systemic lupus erythematosus: Current understanding and future directions.中性粒细胞在神经精神性系统性红斑狼疮中的作用研究进展:目前的认识与未来方向。
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