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环孢素治疗激素抵抗型自身免疫性溶血性贫血

Cyclosporin in steroid-resistant auto-immune haemolytic anaemia.

作者信息

Dündar S, Ozdemir O, Ozcebe O

机构信息

Hacettepe University, School of Medicine Department of Haematology, Ankara, Turkey.

出版信息

Acta Haematol. 1991;86(4):200-2. doi: 10.1159/000204834.

Abstract

A case of Evans' syndrome which was refractory to conventional and high dose steroid treatment and to splenectomy was treated with cyclosporin, beginning with the dose of 10 mg/kg/day and then gradually tapering to 4 mg/kg/day. The patient experienced excellent benefit from cyclosporin; his haematological parameters were completely normal at the 12th month of therapy, without any side effect of the drug.

摘要

1例对传统及大剂量类固醇治疗和脾切除术均无效的伊文氏综合征患者,接受了环孢素治疗,起始剂量为10毫克/千克/天,然后逐渐减至4毫克/千克/天。该患者从环孢素治疗中获益显著;在治疗的第12个月时,其血液学参数完全正常,且未出现该药物的任何副作用。

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