金纳米颗粒对精子的影响：首份全球报告。
Effect of gold nanoparticles on spermatozoa: the first world report.
作者信息
Wiwanitkit Viroj, Sereemaspun Amornpun, Rojanathanes Rojrit
机构信息
Department of Clinical Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
出版信息
Fertil Steril. 2009 Jan;91(1):e7-8. doi: 10.1016/j.fertnstert.2007.08.021. Epub 2007 Dec 11.
OBJECTIVE
To evaluate the spermatotoxicity of gold nanoparticles.
DESIGN
Experimental study.
SETTING
A university in Thailand.
PATIENT(S): Single-donor fresh semen sample.
INTERVENTION(S): A mixture of gold nanoparticle solution and semen was prepared and further analyzed.
MAIN OUTCOME MEASURE(S): Spermatozoa appearance.
RESULT(S): After mixing the semen with a gold nanoparticle solution, 25% of sperm were not motile. Penetration of gold nanoparticle into the sperm heads and tails was observed.
CONCLUSION(S): Spermatotoxicity of the gold nanoparticle can be detected.
目的
评估金纳米颗粒的精子毒性。
设计
实验研究。
地点
泰国一所大学。
患者
单供体新鲜精液样本。
干预措施
制备金纳米颗粒溶液与精液的混合物并进一步分析。
主要观察指标
精子外观。
结果
精液与金纳米颗粒溶液混合后，25%的精子无运动能力。观察到金纳米颗粒穿透精子头部和尾部。
结论
可检测到金纳米颗粒的精子毒性。
Zotero 插件