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急诊室的明信片:一项关于医院治疗自我中毒的随机对照试验的24个月结果

Postcards from the EDge: 24-month outcomes of a randomised controlled trial for hospital-treated self-poisoning.

作者信息

Carter Gregory L, Clover Kerrie, Whyte Ian M, Dawson Andrew H, D'Este Catherine

机构信息

Department of Consultation-Liaison Psychiatry, Locked Bag 7, Hunter Region Mail Centre, NSW 2310, Australia.

出版信息

Br J Psychiatry. 2007 Dec;191:548-53. doi: 10.1192/bjp.bp.107.038406.

Abstract

BACKGROUND

Repetition of self-poisoning is common.

AIMS

To report the 24-month outcomes of a non-obligatory postcard intervention (plus treatment as usual) compared with treatment as usual.

METHOD

In a randomised-controlled trial (Zelen design) conducted in Newcastle, Australia, eight postcards were sent to participants over a 12-month period. The principal outcomes were the proportion of participants with one or more repeat episodes of self-poisoning and the number of repeat episodes per person.

RESULTS

No significant reduction was observed in the proportion of people repeating self-poisoning in the intervention group (21.2%, 95% CI 17.0-25.3) compared with the control group (22.8%, 95% CI 18.7-27.0; chi(2)=0.32, d.f.=1, P=0.57); the difference between groups was -1.7% (95% CI -7.5 to 4.2). There was a significant reduction in the rate of repetition, with an incidence risk ratio of 0.49 (95% CI 0.33-0.73).

CONCLUSIONS

A postcard intervention maintained the halving of the rate of repetition of hospital-treated self-poisoning events over a 2-year period, although it did not significantly reduce the proportion of individuals who repeated self-poisoning.

摘要

背景

重复自我中毒的情况很常见。

目的

报告非强制性明信片干预(加常规治疗)与常规治疗相比的24个月结果。

方法

在澳大利亚纽卡斯尔进行的一项随机对照试验(泽伦设计)中,在12个月内给参与者发送了八张明信片。主要结果是有一次或多次重复自我中毒发作的参与者比例以及每人的重复发作次数。

结果

与对照组(22.8%,95%可信区间18.7 - 27.0;卡方 = 0.32,自由度 = 1,P = 0.57)相比,干预组重复自我中毒的人群比例未观察到显著降低(21.2%,95%可信区间17.0 - 25.3);组间差异为 -1.7%(95%可信区间 -7.5至4.2)。重复率有显著降低,发病风险比为0.49(95%可信区间0.33 - 0.73)。

结论

明信片干预在2年期间使医院治疗的自我中毒事件重复率减半,尽管它没有显著降低重复自我中毒个体的比例。

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