Frye Richard E, Rotenberg Alexander, Ousley Molliann, Pascual-Leone Alvaro
Department of Pediatrics, Division of Child Neurology, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
J Child Neurol. 2008 Jan;23(1):79-96. doi: 10.1177/0883073807307972. Epub 2007 Dec 3.
Transcranial magnetic stimulation (TMS) is a method for focal brain stimulation based on the principle of electromagnetic induction, where small intracranial electric currents are generated by a powerful, rapidly changing extracranial magnetic field. Over the past 2 decades TMS has shown promise in the diagnosis, monitoring, and treatment of neurological and psychiatric disease in adults, but has been used on a more limited basis in children. We reviewed the literature to identify potential diagnostic and therapeutic applications of TMS in child neurology and also its safety in pediatrics. Although TMS has not been associated with any serious side effects in children and appears to be well tolerated, general safety guidelines should be established. The potential for applications of TMS in child neurology and psychiatry is significant. Given its excellent safety profile and possible therapeutic effect, this technique should develop as an important tool in pediatric neurology over the next decade.
经颅磁刺激(TMS)是一种基于电磁感应原理的局灶性脑刺激方法,强大且快速变化的颅外磁场会在颅内产生小电流。在过去20年中,TMS在成人神经和精神疾病的诊断、监测及治疗方面已显示出前景,但在儿童中的应用则较为有限。我们回顾了相关文献,以确定TMS在儿童神经病学中的潜在诊断和治疗应用及其在儿科中的安全性。尽管TMS在儿童中尚未发现任何严重副作用,且似乎耐受性良好,但仍应制定通用的安全指南。TMS在儿童神经病学和精神病学中的应用潜力巨大。鉴于其良好的安全性和可能的治疗效果,这项技术在未来十年应发展成为儿科神经病学中的一项重要工具。