慢性完全性失语症患者经重复经颅磁刺激治疗后命名能力改善——病例报告
Improved naming after TMS treatments in a chronic, global aphasia patient--case report.
作者信息
Naeser Margaret A, Martin Paula I, Nicholas Marjorie, Baker Errol H, Seekins Heidi, Helm-Estabrooks Nancy, Cayer-Meade Carol, Kobayashi Masahito, Theoret Hugo, Fregni Felipe, Tormos Jose Maria, Kurland Jacquie, Doron Karl W, Pascual-Leone Alvaro
机构信息
Harold Goodglass Boston University Aphasia Research Center, Department of Neurology, Boston University School of Medicine and the Veterans Affairs Boston Healthcare System, Boston, Massachusetts 02130, USA.
出版信息
Neurocase. 2005 Jun;11(3):182-93. doi: 10.1080/13554790590944663.
Abstract
We report improved ability to name pictures at 2 and 8 months after repetitive transcranial magnetic stimulation (rTMS) treatments to the pars triangularis portion of right Broca's homologue in a 57 year-old woman with severe nonfluent/global aphasia (6.5 years post left basal ganglia bleed, subcortical lesion). TMS was applied at 1 Hz, 20 minutes a day, 10 days, over a two-week period. She received no speech therapy during the study. One year after her TMS treatments, she entered speech therapy with continued improvement. TMS may have modulated activity in the remaining left and right hemisphere neural network for naming.
摘要
我们报告了一名57岁患有严重非流利性/完全性失语症（左侧基底节出血后6.5年，皮层下病变）的女性，在对右侧布洛卡同源区三角部进行重复经颅磁刺激（rTMS）治疗后2个月和8个月时，其图片命名能力有所改善。rTMS以1赫兹的频率，每天20分钟，共10天，在两周内进行。在研究期间她未接受言语治疗。rTMS治疗一年后，她开始接受言语治疗，病情持续改善。rTMS可能调节了剩余的左右半球神经网络中与命名相关的活动。
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Improved picture naming in chronic aphasia after TMS to part of right Broca's area: an open-protocol study.经颅磁刺激右侧布洛卡区部分区域后慢性失语症患者图片命名能力改善：一项开放协议研究。
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