Ridding Michael C, Rothwell John C
Research Centre for Human Movement Control, Discipline of Physiology, University of Adelaide, Adelaide 5005, Australia.
Nat Rev Neurosci. 2007 Jul;8(7):559-67. doi: 10.1038/nrn2169.
Repetitive transcranial magnetic stimulation (rTMS) has in recent years been used to explore therapeutic opportunities in a bewildering variety of conditions. Although there is good evidence that this technique can modify cortical activity, the rationale for its use in many of the conditions investigated so far is not clear. Here we discuss the effects of rTMS in healthy subjects and how it has been used in a number of neurological conditions. We argue that a better understanding of both the effects of rTMS and the pathological processes underlying the conditions for which it is used will reveal whether rTMS really does offer therapeutic potential and, if so, for which conditions.
近年来，重复经颅磁刺激（rTMS）已被用于探索在各种令人困惑的病症中的治疗机会。尽管有充分的证据表明该技术可以改变皮质活动，但到目前为止，其在许多所研究病症中的使用原理尚不清楚。在此，我们讨论rTMS对健康受试者的影响，以及它在多种神经系统疾病中的应用方式。我们认为，更好地理解rTMS的作用以及其应用病症背后的病理过程，将揭示rTMS是否真的具有治疗潜力，如果有，适用于哪些病症。
