雷特综合征：近期研究进展

Rett syndrome: recent research progress.

作者信息

Percy Alan K

机构信息

Department of Pediatrics, University of Alabama at Birmingham, AL 35294-0021, USA.

出版信息

J Child Neurol. 2008 May;23(5):543-9. doi: 10.1177/0883073807309786. Epub 2007 Dec 3.

DOI:10.1177/0883073807309786

PMID:18056689

Abstract

Recent progress in our understanding of Rett syndrome has been dramatic. Against the background that the clinical features of Rett syndrome may be reversible, in part or in whole, substantial optimism has emerged regarding possible therapies. As such, it is timely to update recent research progress. This update summarizes research advances during the past 18 to 24 months in terms of clinical and translational research, as well as basic research.

摘要

我们对雷特综合征的理解近来取得了显著进展。在雷特综合征的临床特征可能部分或全部可逆的背景下，人们对可能的治疗方法产生了极大的乐观情绪。因此，及时更新近期的研究进展很有必要。本更新总结了过去18至24个月在临床和转化研究以及基础研究方面的研究进展。