Pavlovich N V, Mishan'kin B N, Tynkevich N K, Ryzhko I V, Romanova L V, Danilevskaia G I
Antibiot Khimioter. 1991 Oct;36(10):23-5.
With a large collection of the strains of F. tularensis isolated it has been recently shown that cultures belonging to holarctica and mediaasiatica circulate in the endemic foci of the USSR. By their biological and genetic properties the natural strains of F. tularensis were homogeneous and represented type cultures of F. tularensis. Various ecological conditions in the natural environment did not change within the last 20 years the sensitivity of the tularemia microbe to the antibacterial drugs.
随着大量分离出的土拉弗朗西斯菌菌株的积累，最近已表明，属于全北区和中亚细亚区的培养物在苏联的地方病疫源地中传播。从生物学和遗传学特性来看，土拉弗朗西斯菌的自然菌株是同质的，代表了土拉弗朗西斯菌的典型培养物。在过去20年里，自然环境中的各种生态条件并未改变兔热病微生物对抗菌药物的敏感性。
