Santoro E, Garofalo A, Scutari F A, Carlini M, Zanarini T, Santoro E
Service de Chirurgie, Instituto Regina Elena, Rome, Italie.
Ann Gastroenterol Hepatol (Paris). 1991 Jun;27(4):167-71.
This study presents the results achieved in 2,000 patients who underwent gastric resection and who had been selected from amongst 3,074 cases of gastric neoplasia included in the Retrospective Study of Carcinoma of the Stomach, carried out by the "Italian Stomach Cancer Group" of the Association of Italian Hospital Surgeons (ACOI). In terms of the UICC TNM classification, these patients consisted of 234 stage I patients, 494 stage II patients 1,011 stage III patients and 261 stage IV patients. The overall operative mortality was 7.1 percent. This was lower after subtotal distal resection. The long-term survival tended to fall in proportion with the stage of the illness, whereas the degree of the exeresis did not appear to have any impact. The overall survival at 5 years in the patients who survived the operation was 45%, that following distal resection was 54% and that after total gastrectomy was 33%. The survival rate in terms of the stage ranged from 86% for Early Gastric Cancers to 28% for the patients who underwent surgery at stage III i.e. when they had metastatic lymph nodes.
本研究呈现了2000例接受胃切除术患者的研究结果,这些患者选自意大利医院外科医生协会(ACOI)的“意大利胃癌研究组”开展的胃癌回顾性研究中纳入的3074例胃肿瘤病例。按照国际抗癌联盟(UICC)TNM分类,这些患者包括234例I期患者、494例II期患者、1011例III期患者和261例IV期患者。总体手术死亡率为7.1%。远端次全切除术后的死亡率更低。长期生存率倾向于随着疾病分期而下降,而切除程度似乎没有任何影响。术后存活患者的5年总生存率为45%,远端切除术后为54%,全胃切除术后为33%。按分期的生存率从早期胃癌的86%到III期(即有转移性淋巴结)接受手术患者的28%不等。