人心果种子中的皂苷。

Saponins from the seeds of Achras sapota.

作者信息

Ahmed Rehana, Rashid Fahima, Ahmed Viqar Uddin, Mohammad Faryal Vali, Noorwala Mushtaq, Bibi Nazia, Kazmi Shahana Urooj

机构信息

Department of Chemistry, Faculty of Science, University of Karachi, Karachi, Pakistan.

出版信息

J Asian Nat Prod Res. 2008 Jan-Feb;10(1-2):7-16. doi: 10.1080/10286020701276026.

DOI:10.1080/10286020701276026

PMID:18058375

Abstract

A new pentacyclic triterpenoid saponin (2) along with one known was isolated from the cotyledons of Achras sapota. Their structures were determined with the help of (1)H NMR, (13)C NMR and MS spectral data. The isolated compounds were named as 3-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl-28-O-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranosyl protobassic acid (1) and 3-O-beta-D-glucopyranosyl-(1-->3)-beta-D-glucopyranosyl-28-O-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranosyl-16alpha-hydroxy protobassic acid (2). Compound 2 showed antibacterial activity against Gram positive and negative bacteria.

摘要

从人心果的子叶中分离出一种新的五环三萜皂苷（2）以及一种已知的皂苷。借助¹H NMR、¹³C NMR和MS光谱数据确定了它们的结构。分离出的化合物分别命名为3 - O - β - D - 吡喃葡萄糖基 -（1→6）- β - D - 吡喃葡萄糖基 - 28 - O - α - L - 鼠李吡喃糖基 -（1→3）- β - D - 吡喃木糖基 -（1→4）- α - L - 鼠李吡喃糖基 -（1→2）- α - L - 阿拉伯吡喃糖基原巴西酸（1）和3 - O - β - D - 吡喃葡萄糖基 -（1→3）- β - D - 吡喃葡萄糖基 - 28 - O - α - L - 鼠李吡喃糖基 -（1→3）- β - D - 吡喃木糖基 -（1→4）- α - L - 鼠李吡喃糖基 -（1→2）- α - L - 阿拉伯吡喃糖基 - 16α - 羟基原巴西酸（2）。化合物2对革兰氏阳性和阴性细菌均显示出抗菌活性。