Ibrahim Abdulsalam Saif, Almohammed Ahmed Ali, Allangawi Mona Hassan, A Sattar Hisaham A Aleem, Mobayed Hassan Said, Pannerselvam Balamurugan, Philipose Mary V
Department of Medicine, Hamad Medical Corporation, Doha, Qatar.
Ann Saudi Med. 2007 Nov-Dec;27(6):421-6. doi: 10.5144/0256-4947.2007.421.
Snoring is a commong problem that poses a high risk for obstructive sleep apnea (OSA). We studied the contribution of risk factors for OSA in snorers for full-night polysomnography (PSG).
A questionnaire was administered to subjects referred for PSG in the period from April 2002 to March 2005.
There were 191 (84%) snorers identified by 227 PSG studies. They had a mean age of 48.1+/-9.8 years, (age range, 23-73 years) and 78.5% were males. OSA as indicated by a respiratory disturbance index (RDI) of >5 events/hour was seen in 126 (66%) subjects. In males, 72.7% had OSA, with a mean RDI of 43.0+/-26 events/hour, versus 41.5% [corrected] with OSA in females with a mean RDI of 27.8+/-26.5 events/hour (P<0.001). The OSA group had a higher mean Epworth Sleepiness Scale (ESS) (P<0.001), a larger mean neck circumference (P<0.01), an increased mean age (P<0.050), and more witnessed apneas (P<0.001) but not choking (P=0.096). The mean increase in body mass index was linked to OSA only in females (P<0.05) but not in the overall study (P=0.507). Multivariate analysis showed that ESS, male gender, and a history of witnessed apneas were associated with OSA, while controlling for obesity, large neck circumference, age, and history of choking.
In screening snorers for PSG, male gender, ESS and a history of witnessed apneas were the most important predictors of OSA, but other factors should be considered in referring snorers for PSG. In males, obesity did not contribute to the risk of OSA in our study population.
打鼾是一个常见问题，对阻塞性睡眠呼吸暂停（OSA）构成高风险。我们研究了打鼾者中OSA风险因素对全夜多导睡眠图（PSG）的影响。
对2002年4月至2005年3月期间接受PSG检查的受试者进行问卷调查。
227项PSG研究中识别出191名（84%）打鼾者。他们的平均年龄为48.1±9.8岁（年龄范围23 - 73岁），78.5%为男性。呼吸紊乱指数（RDI）>5次/小时表明存在OSA的情况在126名（66%）受试者中出现。在男性中，72.7%患有OSA，平均RDI为43.0±26次/小时，而女性中41.5%[校正后]患有OSA，平均RDI为27.8±26.5次/小时（P<0.001）。OSA组的平均爱泼沃斯嗜睡量表（ESS）更高（P<0.001），平均颈围更大（P<0.01），平均年龄增加（P<0.050），且观察到的呼吸暂停更多（P<0.001）但窒息情况无差异（P = 0.096）。体重指数的平均增加仅在女性中与OSA相关（P<0.05），但在总体研究中无相关性（P = 0.507）。多变量分析表明，在控制肥胖、颈围大、年龄和窒息史的情况下，ESS、男性性别和观察到的呼吸暂停史与OSA相关。
在为打鼾者筛查PSG时，男性性别、ESS和观察到的呼吸暂停史是OSA最重要的预测因素，但在推荐打鼾者进行PSG检查时应考虑其他因素。在我们的研究人群中，肥胖对男性的OSA风险无影响。
