Pintor María Fernanda, Figueroa Liberto, Martínez Benjamín
Servicio de Cirugía Máxilo-Facial, Clínica Alemana de Santiago, Chile.
Med Oral Patol Oral Cir Bucal. 2007 Dec 1;12(8):E549-51.
Polymorphous Low-Grade Adenocarcinoma is a rare, malignant salivary gland tumor, which is found almost exclusively in minor salivary glands. It is more frequent in the age range from 30 to 70, with a clear female predilection in a 2:1 ratio. It is usually located in the hard or soft palate, although it may be found in the rest of the oral cavity too. It is rare in major salivary glands. In general it has good prognosis, with recurrence rates in the range of 17% - 24%. Although rare, metastasis to regional lymph nodes may occur in 9% of the cases. This report describes the case of a patient that consulted at the Military Odontological Center (Central Odontológica del Ejército) due to an esthetic alteration of her dental prosthesis, which had been made 8 years before. The patient was sent to the Maxillofacial Surgery Service, where the intraoral examination showed a big mass compromising the hard palate and the alveolar ridge. During examination, a dent in her prosthesis was found to correspond to the tumor mass; it was therefore concluded that the tumor had at least an eight-year-old evolution. An incisional biopsy was carried out, and once the polymorphous low-grade adenocarcinoma diagnosis had been stated, the patient was sent to the Head and Neck Surgery Service of the Military Hospital, where the lesion was treated by wide surgical excision followed by radiation therapy.
多形性低度恶性腺癌是一种罕见的涎腺恶性肿瘤，几乎仅见于小涎腺。发病年龄多在30至70岁之间，女性明显多于男性，比例约为2:1。通常位于硬腭或软腭，不过也可能出现在口腔其他部位。在大涎腺中较为罕见。总体预后良好，复发率在17% - 24%之间。虽然少见，但9%的病例可能会发生区域淋巴结转移。本报告描述了一名患者的病例，该患者因8年前制作的假牙美观改变而前往军事牙科中心（陆军牙科中心）就诊。患者被转诊至颌面外科，口腔检查发现一个大肿块累及硬腭和牙槽嵴。检查期间，发现假牙上的一处凹陷与肿瘤肿块相对应，因此推断肿瘤至少已有8年的发展历程。进行了切开活检，在确诊为多形性低度恶性腺癌后，患者被送往军事医院头颈外科，通过广泛手术切除并辅以放射治疗对病变进行治疗。
