Perasso A, Testino G
Divisione di Gastroenterologia ed Endoscopia Digestiva, Ospedale San Martino, Genova.
Minerva Gastroenterol Dietol. 1991 Oct-Dec;37(4):199-204.
Aim of this experience has been to evaluate the behavior of the chief cell mass, of the parietal cell mass and of the serum pepsinogen I in patients operated on for duodenal ulcer by the Billroth II compared to patients with chronic fundic gastritis in non operated stomach and to healthy controls. From the results, even in operated patients, emerges a progressive reduction of the two cell masses, in relation to the different degree of chronic gastritis of the stump, in analogy with chronic fundic gastritis in non-operated stomach. In chronic superficial gastritis no differences emerge between operated patients and patients with chronic superficial fundic gastritis in non operated stomach, while with the getting on the inflammation, it can be observed a higher fall of the parietal cell mass in operated subjects than in non operated ones. Such differences are even greater in relation with the evaluation of the time elapsed between the operation and the evaluation of the two cell masses. Furthermore, no significant differences have emerged between the two groups of patients as for serum pepsinogen I. Such data is not discriminant between the two conditions.
本次实验的目的是评估接受毕Ⅱ式手术治疗十二指肠溃疡的患者，与未接受手术的慢性胃底胃炎患者及健康对照组相比，主细胞团、壁细胞团以及血清胃蛋白酶原I的表现。从结果来看，即使是接受手术的患者，与未接受手术的胃中慢性胃底胃炎类似，随着残端慢性胃炎程度的不同，这两种细胞团也会逐渐减少。在慢性浅表性胃炎中，接受手术的患者与未接受手术的慢性浅表性胃底胃炎患者之间没有差异，然而随着炎症进展，可以观察到接受手术的受试者壁细胞团的下降幅度高于未接受手术的受试者。就手术与评估这两种细胞团之间的时间间隔而言，这种差异甚至更大。此外，两组患者在血清胃蛋白酶原I方面没有显著差异。这些数据无法区分这两种情况。
