[Characteristics and relationship of mitochondrial and microsomal oxidation processes with various intensities of lipid peroxidation].

Mitochondrial and microsomal oxidation reactions were studied at varying intensities of lipid peroxidation (LPO). The latter were modelled by using thermal burn and combined radiation-thermal injury in animals. It was found that the differences in the intensity and duration of free radical oxidation and LPO reactions may lead to the activation or inhibition of mitochondrial respiration due to the oxidative phosphorylation uncoupling and impaired microsomal and microsomal-mitochondrial intermembrane electron transport and depend on the activities of superoxide dismutase, glutathione reductase and catalase.