Markland Alayne D, Kraus Stephen R, Richter Holly E, Nager Charles W, Kenton Kimberly, Kerr Lindsey, Xu Yan
Division of Gerontology, Geriatrics, and Palliative Care, Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35233, USA.
Am J Obstet Gynecol. 2007 Dec;197(6):662.e1-7. doi: 10.1016/j.ajog.2007.08.062.
The objective of the study was to determine the prevalence and identify potential risk factors for monthly fecal incontinence (FI) in women presenting for stress urinary incontinence (UI) surgery.
From 655 women enrolled in the Stress Incontinence Surgical Treatment Efficacy Trial, baseline data were analyzed. FI was defined as occurring at least monthly. Independent variables included sociodemographics, health status and history, physical examination, and validated UI questionnaires. Multivariable logistic regression models compared women with FI with women with only UI.
Prevalence of monthly FI was 16%, 10% for liquid stool, and 6% for solid stool. In multivariable analysis, increased risk of FI was associated (odds ratio, 95% confidence interval) with decreased anal sphincter contraction (4.5, 2.0 to 10.4), perimenopausal status (2.4, 1.1 to 5.0), prior incontinence surgery/treatment (1.8, 1.1 to 2.9), and increased UI bother (1.1, 1.1 to 1.2).
Women enrolled in a stress UI surgical trial have high rates of monthly FI and further evaluation of FI symptoms may be warranted.
本研究的目的是确定因压力性尿失禁（UI）手术就诊的女性每月粪便失禁（FI）的患病率，并识别潜在风险因素。
对参与尿失禁手术治疗疗效试验的655名女性的基线数据进行分析。FI定义为至少每月发生一次。自变量包括社会人口统计学、健康状况和病史、体格检查以及经过验证的UI问卷。多变量逻辑回归模型将患有FI的女性与仅患有UI的女性进行比较。
每月FI的患病率为16%，其中液体粪便为10%，固体粪便为6%。在多变量分析中，FI风险增加与以下因素相关（比值比，95%置信区间）：肛门括约肌收缩减弱（4.5，2.0至10.4）、围绝经期状态（2.4，1.1至5.0）、既往失禁手术/治疗（1.8，1.1至2.9）以及UI困扰增加（1.1，1.1至1.2）。
参与压力性UI手术试验的女性每月FI发生率较高，可能需要对FI症状进行进一步评估。
