Collins Margaret H
Department of Pathology, University of Cincinnati, Cincinnati, Ohio 45221, USA.
Gastrointest Endosc Clin N Am. 2008 Jan;18(1):59-71; viii-ix. doi: 10.1016/j.giec.2007.09.014.
The pathology of eosinophilic esophagitis (EE) when fully developed in humans is highly characteristic and readily discriminated from the histology of the normal esophagus. The histologic alterations are not pathognomonic for any of the multiple causes of EE, and the correct diagnosis can be made only if the histology is correlated with clinical findings. The histology of the normal esophagus is reviewed and contrasted with the findings in EE. The characteristic findings in EE are illustrated. Selected research in humans and animal models pertinent to EE are briefly reviewed.
嗜酸性食管炎（EE）在人类中充分发展时的病理学具有高度特征性，很容易与正常食管的组织学区分开来。这些组织学改变并非EE多种病因中的任何一种所特有的，只有当组织学与临床发现相关联时才能做出正确诊断。本文回顾了正常食管的组织学，并将其与EE的发现进行对比。展示了EE的特征性发现。简要回顾了与EE相关的人类和动物模型的部分研究。
