Assa'ad Amal
Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 2000, Cincinnati, OH 45229, USA. amal.assa'
Gastrointest Endosc Clin N Am. 2008 Jan;18(1):119-32; x. doi: 10.1016/j.giec.2007.09.001.
Atopy has been linked to eosinophilic gastrointestinal disorders because of the role eosinophils play in atopic disorders. It has also been found that these disorders coexist. The goal of this article is to take a step back, and considering only eosinophilic esophagitis, attempt to determine from the available body of clinical and research literature: (1) Is the coexistence of these disorders attributable to a preconceived bias? If so, what is the source of the bias and how can it be removed? (2) Is there a cause and effect relationship? If so, can this relationship be harnessed for diagnostic and therapeutic modalities?
由于嗜酸性粒细胞在特应性疾病中所起的作用，特应性已与嗜酸性粒细胞性胃肠道疾病相关联。人们还发现这些疾病并存。本文的目的是退一步，仅考虑嗜酸性粒细胞性食管炎，尝试从现有的临床和研究文献中确定：（1）这些疾病的并存是否归因于先入为主的偏见？如果是，偏见的来源是什么，如何消除？（2）是否存在因果关系？如果是，这种关系能否用于诊断和治疗方法？
