Olgar Seref, Ertugrul Turkan, Devecioglu Omer, Nisli Kemal, Omeroglu Rukiye Eker
Pediatric Cardiology Unit, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
J Rheumatol. 2007 Dec;34(12):2491-4.
Macrophage activation syndrome (MAS) is a major cause of death in patients with systemic juvenile idiopathic arthritis (JIA). We describe 4 patients who developed MAS during or after vancomycin treatment. Vancomycin should be used with great care in patients with systemic JIA.
巨噬细胞活化综合征(MAS)是系统性幼年特发性关节炎(JIA)患者死亡的主要原因。我们描述了4例在万古霉素治疗期间或之后发生MAS的患者。对于系统性JIA患者,应极其谨慎地使用万古霉素。