Dunicz-Sokolowska Aldona, Wlaźlak Edyta, Surkont Grzegorz, Radomska Krystyna, Długaszek Maria, Graczyk Alfreda
Polish Academy of Sciences, System Research Institute, ul. Newelska 6, 01-447 Warsaw, Poland.
Magnes Res. 2007 Jun;20(2):136-47.
The aim of this study was to define referential values of 5 basic bioelements (Ca, Mg, Zn, Cu, Fe) and 2 toxic metals (Pb and Cd) in the hair of Polish adults aged 40 to 60 years, based on the research conducted from 1991 to 2006 on a group of 3349 formally healthy women and men. The results of our biochemical tests were subjected to statistical analysis and they can be treated as referential norms for the concentrations of analyzed bioelements in the hair of Polish population. Our analyses confirm significant differences in accumulations of certain elements (Ca, Mg, Zn) in women's and men's hair. The hair element analysis of the tested women population indicates the age 49-50 as the one in which a significant decrease of hair Ca and Zn begins. Marked decrease of Ca and Zn in men begins 2-3 years later than in women. A slight tendency to decrease hair Mg in women and men during the period observed of 40-60 years of age was noticed. Significant differences (alpha = 0.05) between hair Cu contents in women and men were not observed. The increase of variances of hair Fe concentrations in women, especially after 50, has been observed. Significantly higher hair Pb and Cd concentrations were shown in men. The analysis of correlation confirms the significance (p < 0.050000) of synergistic interactions between bioelements: Ca-Mg (r = +0.7635), Ca-Zn (r = +0.36), Ca-Cu (r = +0.124), Ca-Fe (r = +0.054), Mg-Zn (r = +0.35), Mg-Cu (r = +0.11), Mg-Fe (r = +0.0757), Zn-Cu (r = +0.11), Cu-Fe (r = +0.0765). Significance (p < 0.050000) of antagonistic interactions of bioelements with toxic metals: Ca-Pb (r = -0.0965), Zn-Pb (r = -0.2476), Mg-Pb (r = -0.13), Zn-Cd (r = -0.0889) was established. Significance (p < 0.050000) of synergistic effects with toxic metals: Pb-Cd (r = +0.3322), Cu-Pb (r = +0.09), Fe-Pb (r = +0.1413), Fe-Cd (r = +0.1161) was confirmed. Adults in whose hair bioelements and hair toxic metal concentrations have shown values outlying from reference and who have too much toxic elements and too little bioelements should undergo further diagnostic tests since these results could be a sign of disturbances, that could lead to various diseases.
本研究的目的是，基于1991年至2006年对3349名表面健康的成年男女进行的研究，确定40至60岁波兰成年人头发中5种基本生物元素（钙、镁、锌、铜、铁）和2种有毒金属（铅和镉）的参考值。我们生化测试的结果经过了统计分析，可作为波兰人群头发中所分析生物元素浓度的参考标准。我们的分析证实，女性和男性头发中某些元素（钙、镁、锌）的积累存在显著差异。对受试女性人群的头发元素分析表明，49 - 50岁时头发中的钙和锌开始显著减少。男性头发中钙和锌的显著减少比女性晚2 - 3年。在40 - 60岁的观察期内，注意到女性和男性头发中的镁有轻微下降趋势。未观察到女性和男性头发中铜含量的显著差异（α = 0.05）。观察到女性头发中铁浓度的方差增加，尤其是在50岁以后。男性头发中的铅和镉浓度显著更高。相关性分析证实了生物元素之间协同相互作用的显著性（p < 0.050000）：钙 - 镁（r = +0.7635）、钙 - 锌（r = +0.36）、钙 - 铜（r = +0.124）、钙 - 铁（r = +0.054）、镁 - 锌（r = +0.35）、镁 - 铜（r = +0.11）、镁 - 铁（r = +0.0757）、锌 - 铜（r = +0.11）、铜 - 铁（r = +0.0765）。生物元素与有毒金属拮抗相互作用的显著性（p < 0.050000）：钙 - 铅（r = -0.0965）、锌 - 铅（r = -0.2476）、镁 - 铅（r = -0.13）、锌 - 镉（r = -0.0889）已得到证实。与有毒金属协同效应的显著性（p < 0.050000）：铅 - 镉（r = +0.3322）、铜 - 铅（r = +0.09）、铁 - 铅（r = +0.1413）、铁 - 镉（r = +0.1161）也得到了证实。头发中生物元素和有毒金属浓度显示的值偏离参考值，且有毒元素过多而生物元素过少的成年人应接受进一步的诊断测试，因为这些结果可能是紊乱的迹象，可能导致各种疾病。
