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[视网膜色素变性的免疫学变化及其与中医辨证的关系]

[Immunological change in pigmentary degeneration of retina and its relation to traditional Chinese medicine differentiation of syndromes].

作者信息

Qin Y H, Zhu W F, Li C K

机构信息

Hunan Academy of TCM and Medicinal Herbs, Changsha.

出版信息

Zhong Xi Yi Jie He Za Zhi. 1991 Oct;11(10):600-2, 581.

PMID:1806306
Abstract

Using monoclonal antibody technique, T lymphocyte cell subgroups, immunoglobins, complements, and circulating immune complexes (CIC) were measured in 60 patients with pigmentary degeneration of retina (RP) and 40 normal subjects. The results indicated that T1, T4, T8, C3 and C4 of the patients were lower than those of the controls; T4/T8, IgM and CIC of the patients were more than those of the controls. The differences between the patients and the controls were remarkably significant. Similarly, by investigating the objective quota of TCM differentiation of syndromes, the authors divided the RP patients into Liver-Kidney deficiency of Yin and Spleen-Kidney deficiency of Yang groups, and compared them with normal subjects. The results indicated that the two groups underwent similar change of immunology. But they had their own characteristics. The Yin-deficiency group showed remarkable increase of T4/T8 and normal T4; the Yang-deficiency group showed remarkable reduction of T1 and reduction of T4.

摘要

采用单克隆抗体技术,对60例视网膜色素变性(RP)患者和40例正常对照者检测了T淋巴细胞亚群、免疫球蛋白、补体及循环免疫复合物(CIC)。结果显示,患者的T1、T4、T8、C3和C4低于对照组;患者的T4/T8、IgM和CIC高于对照组。患者与对照组之间差异非常显著。同样,通过调查中医辨证的客观指标,作者将RP患者分为肝肾阴虚组和脾肾阳虚组,并与正常对照者进行比较。结果表明,两组的免疫学变化相似,但各有特点。阴虚组T4/T8显著升高,T4正常;阳虚组T1显著降低,T4降低。

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