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[慢性再生障碍性贫血的中医辨证;外周血T淋巴细胞亚群与红细胞C3b受体]

[Syndrome differentiation in traditional Chinese medicine in chronic aplastic anemia; T-lymphocyte subpopulation in peripheral blood and erythrocyte C3b receptors].

作者信息

Liu B W, Zhang S R, Shi W

机构信息

Affiliated Hospital of Liaoning College of TCM, Shengang.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1992 Apr;12(4):222-3, 197.

PMID:1386768
Abstract

UNLABELLED

In this paper, the Syndrome Differentiation in TCM and the determination on T-lymphocyte subpopulation and RBC C3b receptor were carried out by using indirect SPA assay and RBC C3b receptor ring test among 51 chronic aplastic anemia patients.

RESULT

The OKT3, OKT4 and OKT4/OKT8 ratio in groups of Kidney-Yin Deficiency group were lower, while the OKT8 was higher than that of controls. In the group of both Kidney-Yin and Yang Deficiency, OKT4 and OKT4/OKT8 ratio were lower. and the value of OKT8 is higher than that of controls. The OKT8 in the Kidney-Yang Deficiency group was higher. and the ratio of OKT4/OKT8 was lower than that of controls. The OKT8 in the Kidney-Yin Deficiency group among three groups increased higher than that of other two groups. while the OKT4/OKT8 ratio reduced. The OKT4/OKT8 ratio in the group of both Kidney-Yin and Yang Deficiency was higher than that of Kidney-Yang Deficiency group. Among the three groups, the rosette rates of RBC C3b receptor were lower than controls. The above-mentioned data were statistically significant. These characteristic changes could be used as a reference of microcosmic Syndrome Differentiation and also a guide for how to apply the immunosuppressant and immunopotentiator.

摘要

未标记

本文采用间接SPA试验及红细胞C3b受体花环试验,对51例慢性再生障碍性贫血患者进行了中医辨证及T淋巴细胞亚群和红细胞C3b受体的检测。

结果

肾阴虚组的OKT3、OKT4及OKT4/OKT8比值降低,而OKT8高于对照组。肾阴阳两虚组的OKT4及OKT4/OKT8比值降低,OKT8值高于对照组。肾阳虚组的OKT8升高,OKT4/OKT8比值低于对照组。三组中肾阴虚组的OKT8升高幅度高于其他两组,而OKT4/OKT8比值降低。肾阴阳两虚组的OKT4/OKT8比值高于肾阳虚组。三组的红细胞C3b受体花环率均低于对照组。上述数据具有统计学意义。这些特征性变化可作为微观辨证的参考,也可为免疫抑制剂和免疫增强剂的应用提供指导。

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