Chang Chang-Chi, Kuo Junne-Yih, Chan Wan-Leong, Chen Kuang-Kuo, Chang Luke S
Division of Urology, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2007 Nov;70(11):486-91. doi: 10.1016/S1726-4901(08)70046-7.
We investigated simple renal cysts to understand the prevalence in healthy individuals and evaluate their clinical characteristics to determine whether or not there are any risk factors associated with simple renal cysts.
Abdominal sonography was performed in 577 individuals (317 men, 260 women; mean age, 48.84 years; age range, 20-94 years) who received health check-up in January to February 2005. Data including age, sex, renal sonographic findings (cyst number, site, diameter, renal stones), values of serum cholesterol, glucose and creatinine, urine analysis (proteinuria, hematuria, pyuria), and smoking habit were analyzed.
The overall prevalence of simple renal cysts was 10.7%, ranging from 2.38% in the 2nd to 35.29% in the 7th or later decade of life. The prevalence increased with age (p<0.001). The mean age of individuals with cysts was significantly older than those without cysts (57.65+/-13.35 vs. 47.78+/-12.40 years; p<0.001). Male-to-female ratio was 2.81 (15.14% vs. 5.38%; p<0.001). The majority of cysts were solitary (82.3%). Mean largest diameter of cysts was 20.89+/-12.62 mm. The mean size of cysts in every age group was not statistically different. Factors significantly associated with simple renal cysts were age (odds ratio [OR], 4.37; p<0.001), sex (OR, 0.32; p<0.001), serum creatinine (OR, 11.77; p=0.001), proteinuria (OR, 3.11; p=0.004), renal stone (OR, 2.47; p=0.006), and smoking (OR, 2.80; p<0.001). However, in multivariate analysis, except proteinuria, all of the above factors were significantly related to the occurrence of simple renal cysts.
The overall prevalence of simple renal cysts in healthy individuals was 10.7%. Age, sex, renal stone, serum creatinine, and smoking were found to be risk factors for the presence of simple renal cysts.
我们对单纯性肾囊肿进行了研究，以了解健康个体中的患病率，并评估其临床特征，从而确定是否存在与单纯性肾囊肿相关的任何危险因素。
对2005年1月至2月接受健康检查的577名个体（317名男性，260名女性；平均年龄48.84岁；年龄范围20 - 94岁）进行腹部超声检查。分析的数据包括年龄、性别、肾脏超声检查结果（囊肿数量、位置、直径、肾结石）、血清胆固醇、血糖和肌酐值、尿液分析（蛋白尿、血尿、脓尿）以及吸烟习惯。
单纯性肾囊肿的总体患病率为10.7%，在20多岁时为2.38%，在70岁及以后年龄段为35.29%。患病率随年龄增加而升高（p<0.001）。有囊肿的个体的平均年龄显著高于无囊肿的个体（57.65±13.35岁对47.78±12.40岁；p<0.001）。男女比例为2.81（15.14%对5.38%；p<0.001）。大多数囊肿为单发（82.3%）。囊肿的平均最大直径为20.89±12.62毫米。各年龄组囊肿的平均大小无统计学差异。与单纯性肾囊肿显著相关的因素有年龄（比值比[OR]，4.37；p<0.001）、性别（OR，0.32；p<0.001）、血清肌酐（OR，11.77；p = 0.001）、蛋白尿（OR，3.11；p = 0.004）、肾结石（OR，2.47；p = 0.006）和吸烟（OR，2.80；p<0.001）。然而，在多变量分析中，除蛋白尿外，上述所有因素均与单纯性肾囊肿的发生显著相关。
健康个体中单纯性肾囊肿的总体患病率为10.7%。年龄、性别、肾结石、血清肌酐和吸烟被发现是单纯性肾囊肿存在的危险因素。
