Hayashi Akio, Shiono Hiroyuki, Okumura Meinoshin
Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-2(L5), Yamadaoka, Suita, Osaka, 565-0871, Japan.
Interact Cardiovasc Thorac Surg. 2008 Apr;7(2):347-8. doi: 10.1510/icvts.2007.164178. Epub 2007 Dec 6.
Thymomas are associated at a high frequency with paraneoplastic autoimmune diseases. We treated a 64-year-old male with a thymoma, who also had lichen planus. The tumor was resected and diagnosed as thymoma, however, the symptoms associated with lichen planus did not subside and persisted. A preoperative examination showed an elevated serum level of squamous cell carcinoma antigen, which gradually decreased to normal after surgery. The findings of this case are interesting for understanding the correlation between a thymoma and autoimmune abnormalities.
胸腺瘤常与副肿瘤性自身免疫性疾病高度相关。我们治疗了一名64岁患有胸腺瘤的男性患者,他同时还患有扁平苔藓。肿瘤被切除并诊断为胸腺瘤,然而,与扁平苔藓相关的症状并未消退且持续存在。术前检查显示血清鳞状细胞癌抗原水平升高,术后该水平逐渐降至正常。该病例的发现对于理解胸腺瘤与自身免疫异常之间的相关性具有重要意义。