Jurajda V
Vet Med (Praha). 1976 Feb;21(2):107-18.
In the course of serial passaging of the strain of Marek's disease (MD) (VUB-70) in White Leghorns the author investigated the morbidity, mortality, development of the MD-specific changes, and the effect of sex on these indices, for the purpose of characterization of the biological properties of an isolated strain of MD in vivo. The incubation period lasted from 41 to 46 days p. inf. on the first day of life. Pullets showed greater sensitiveness towards infection not only through higher morbidity and mortality, but also due to a larger number of tumorous changes. In MD-positive animals the same proportion of macroscopic and microscopic changes was found. The average occurrence of Marek's disease amounted to 74.4 p. c. On the basis of the biological properties in vivo the VUB-70 strain was characterized as a medium pathogenic strain of the acute form of Marek's disease.
在白来航鸡中对马立克氏病（MD）毒株（VUB - 70）进行连续传代的过程中，作者研究了发病率、死亡率、MD特异性病变的发展以及性别对这些指标的影响，目的是在体内表征一株分离的MD毒株的生物学特性。潜伏期从感染后第41天持续到第46天，感染发生在鸡出生的第一天。小母鸡不仅通过更高的发病率和死亡率表现出对感染更高的敏感性，而且还由于大量的肿瘤性病变。在MD阳性动物中，发现宏观和微观病变的比例相同。马立克氏病的平均发生率为74.4%。基于体内生物学特性，VUB - 70毒株被表征为马立克氏病急性形式的中等致病力毒株。
