Proctor S J, Sherman K C
Vet Pathol. 1975;12(5-6):362-77. doi: 10.1177/0300985875012005-00603.
Vesicular stomatitis virus was inoculated into the dorsal lingual epithelium of three cows. The reaction that developed in 72 h was characterized by severe acute diffuse glossitis with intercellular edema and necrosis of keratinocytes. Virions budded from the plasma membrane and were in the intercellular spaces. Reduplication of desmosomes was a prominent alteration, and normal desmosomes were within the cytoplasm. Intracytoplasmic desmosomes appeared to be formed by endocytosis after breaks occurred in the plasma membrane of one cell; endocytosis of loops of plasma membrane containing desmosomes; and formation of desmosomes on invagination of the plasma membrane.
将水疱性口炎病毒接种到三头奶牛的舌背上皮中。72小时内出现的反应特征为严重的急性弥漫性舌炎，伴有角质形成细胞的细胞间水肿和坏死。病毒粒子从质膜出芽并存在于细胞间隙中。桥粒的复制是一个显著变化，正常桥粒位于细胞质内。胞质内桥粒似乎是在一个细胞的质膜发生断裂后通过内吞作用形成的；含有桥粒的质膜环的内吞作用；以及质膜内陷处桥粒的形成。
