Wallace A L, McLaughlin B, Weiss J B, Hughes S P
Royal Infirmary of Edinburgh, UK.
Injury. 1991 Sep;22(5):375-6. doi: 10.1016/0020-1383(91)90098-y.
Angiogenesis is an important step in the normal process of fracture healing, irrespective of the method of fixation. Using a quantitative assay, the amount of endothelial cell stimulating factor (ESAF) has been determined in a small group of patients with tibial fractures. ESAF levels were found to be increased when compared with normal volunteers, although this increase was relatively less in fractures held with intramedullary nails than with external fixation.
血管生成是骨折愈合正常过程中的重要一步，与固定方法无关。通过定量分析，已在一小群胫骨骨折患者中测定了内皮细胞刺激因子（ESAF）的含量。与正常志愿者相比，发现ESAF水平有所升高，尽管与外固定相比，髓内钉固定的骨折中这种升高相对较小。
