Fukuda T, Komatsubara H, Kasai T, Tsujimura M
Laboratory of Biological-organic chemistry, Joshi Eiyo University Sakado-shi, Saitama, Japan.
Int J Vitam Nutr Res. 1991;61(4):325-7.
The possible biosynthesis of ascorbic acid 2-sulfate (AsS) in rat was investigated. A in vivo test was conducted according to Mumma and Mohamram. 10 mumoles ascorbic acid (AsA) and 25 mu Ci35SO4(2-) were injected intraperitoneally into rats once a day for four days. 24 hours after the final administration, the animals were sacrificed and the liver, kidneys and urine were collected. The result did not confirm the biosynthesis of AsS under the test conditions, though there appeared the possibility of the biosynthesis of a trace amount of AsS too small to permit detection.
研究了大鼠体内抗坏血酸2 - 硫酸盐(AsS)的可能生物合成。根据穆马和穆罕默拉姆的方法进行了一项体内试验。每天一次向大鼠腹腔注射10微摩尔抗坏血酸(AsA)和25微居里的35SO4(2-),持续四天。在最后一次给药24小时后,处死动物并收集肝脏、肾脏和尿液。结果未证实在所测试的条件下AsS的生物合成,尽管也存在极少量AsS生物合成的可能性,但其量太小无法检测到。