Yu Qiong, Lu Liang, Yu Miao-cheng, Liang Yan-lian, Su Yu-qing, Wang Da-ming
Shenzhen Blood Center, Shenzhen Institute of Transfusion Medicine, Shenzhen, Guangdong, 518035 PR China.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Dec;24(6):652-5.
To study the distribution of ABO gene polymorphism in Uighur population in Xinjiang area of China.
DNA was extracted from 160 Uygur unrelated donorso blood and PCR-sequence specific primer analysis was performed. Some difficult samples were further directly sequenced.
Six alleles were detected in a population of 160 Uighur individuals, the gene frequencies of which were 0.2062(A101), 0.0563(A102), 0.0156(A201), 0.0031(A205),0.1875(B01),0.5312(O01), respectively.
The characteristics for AB gene structure of Xinjiang Uighur suggests that genetic polymorphism is distinguished between Xinjiang Uighur nationality and Chinese Han nationality, and both of them have discrepancy and confluent characters.
研究中国新疆地区维吾尔族人群ABO基因多态性分布情况。
从160名维吾尔族无关献血者中提取DNA，并进行聚合酶链反应-序列特异性引物分析。对部分疑难样本进一步直接测序。
在160名维吾尔族人群中检测到6个等位基因，其基因频率分别为0.2062（A101）、0.0563（A102）、0.0156（A201）、0.0031（A205）、0.1875（B01）、0.5312（O01）。
新疆维吾尔族AB基因结构特点表明，新疆维吾尔族与汉族在遗传多态性上存在差异，同时又具有差异与融合的特征。
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