Holtsmark Ingrid, Eijsink Vincent G H, Brurberg May Bente
Plant Health and Plant Protection Division, Norwegian Institute for Agricultural and Environmental Research, Høgskoleveien, Norway.
FEMS Microbiol Lett. 2008 Mar;280(1):1-7. doi: 10.1111/j.1574-6968.2007.01010.x. Epub 2007 Dec 7.
Many bacteria produce antimicrobial substances such as nonribosomally synthesized antibiotics and ribosomally synthesized proteinaceous compounds referred to as bacteriocins. Secretion of antimicrobials is generally thought to contribute to the competitiveness of the producing organism, but there are indications that these compounds in some cases may have regulatory roles too. Bacteriocins most often act on closely related species only and are thus of interest for application as targeted narrow-spectrum antimicrobials with few side effects. Although the application of bacteriocins in plant disease control is an attractive option, very little is known about the occurrence and roles of these compounds in plant pathogenic bacteria and their natural competitors occurring in the same biotopes. This study presents an overview of current knowledge of bacteriocins from plant pathogenic bacteria.
许多细菌会产生抗菌物质,如非核糖体合成的抗生素和核糖体合成的蛋白质类化合物(即细菌素)。一般认为抗菌物质的分泌有助于产生菌的竞争力,但有迹象表明,在某些情况下,这些化合物可能也具有调节作用。细菌素通常仅作用于密切相关的物种,因此作为副作用少的靶向窄谱抗菌剂具有应用价值。尽管将细菌素应用于植物病害防治是一个有吸引力的选择,但对于这些化合物在植物病原菌及其在同一生态位中的天然竞争者中的存在情况和作用却知之甚少。本研究概述了目前关于植物病原菌细菌素的知识。