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质量如何影响局限性前列腺癌体外放疗的临床结果。

How quality influences the clinical outcome of external beam radiotherapy for localized prostate cancer.

作者信息

van Vulpen Marco, van der Heide Uulke A, van Moorselaar Jeroen R J A

机构信息

Department of Radiation-Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

BJU Int. 2008 Apr;101(8):944-7. doi: 10.1111/j.1464-410X.2007.07346.x. Epub 2007 Dec 7.

Abstract

For the delivery of good-quality external beam radiotherapy (EBRT) in localized prostate cancer, under-dosage to the peripheral zone (tumour) is one likely cause of poor results. The quality is improved by daily verification of the position of the prostate, and the use of magnetic resonance imaging (MRI) in delineation. Currently these are demands on quality that should be incorporated in each radiotherapy department. The use of MRI in staging is also expected to improve patient selection for EBRT. Furthermore, an adequate radiation dose should be delivered. In this overview we describe what the urologist should expect from radiation oncologists to obtain the optimum results for the patients.

摘要

对于局限性前列腺癌的优质外照射放疗(EBRT),外周区(肿瘤)剂量不足是导致治疗效果不佳的一个可能原因。通过每日核实前列腺位置以及在勾画靶区时使用磁共振成像(MRI)可提高治疗质量。目前,这些质量要求应纳入每个放疗科室。预计在分期中使用MRI也将改善EBRT的患者选择。此外,应给予足够的辐射剂量。在本综述中,我们描述了泌尿科医生为使患者获得最佳治疗效果应期望放射肿瘤学家做到什么。

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