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[吉林省长春市双阳区农村原发性闭角型青光眼患病率及其病因分析]

[The prevalence of primary angle-closure glaucoma and its causes in rural area of Shuangyang district in Changchun, Jilin province].

作者信息

Yuan Hui-ping, Yu Hong, Xiao Zheng, Shao Zheng-bo, Zhang Xiao-li, Yang Bin-bin, Sui Hong, Zhao Ya-shuang

机构信息

Department of Ophthalmology, the 2nd Affiliated Hospital, Harbin Medical University, Harbin 150086, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2007 Sep;43(9):775-8.

PMID:18070519
Abstract

OBJECTIVE

To investigate the prevalence of primary angle-closure glaucoma (PACG) and its causes in a rural area in Changchun, China.

METHODS

From the rural area of Qijiaxiang, Shuangyang district of Changchun, 1139 individuals aged 40 years and above were randomly selected for the study from September 2004 to February 2005 using Zhao Jialiang's standard. All subjects in this study underwent a preliminary screening examination including visual acuity, the peripheral depth of anterior chamber, slit lamp, tonometry and fundus. The suspects of PACG were asked to repeat the following examinations: tonometry, gonioscopy, fundus, and visual field assessment.

RESULTS

1139 of 1528 subjects were invited to participate in the study (response rate 74.5%). In those age 40 years and above, the prevalence of PACG was 1.5% in men, 3.5% in women, and 2.5% in general population, respectively. The prevalence was increased with age. The anterior chamber was significantly (P<0.01) narrower in the female group than in the male group when the peripheral depth of anterior chamber was compared. The prevalence of PACG was significantly (P<0.02) higher in subjects with positive family history than with negative family history.

CONCLUSIONS

In the rural area in Shuangyang district of Changchun, the prevalence of PACG is higher than other regions surveyed in China. Sex, age, family history and the peripheral depth of anterior chamber are significant risk factors in PACG.

摘要

目的

调查中国长春某农村地区原发性闭角型青光眼(PACG)的患病率及其病因。

方法

2004年9月至2005年2月,采用赵家良标准,从长春双阳区齐家乡农村地区随机选取1139名40岁及以上个体进行研究。本研究所有受试者均接受了包括视力、前房周边深度、裂隙灯、眼压测量和眼底检查在内的初步筛查。PACG疑似患者被要求重复进行以下检查:眼压测量、房角镜检查、眼底检查和视野评估。

结果

1528名受试者中有1139名被邀请参加研究(应答率74.5%)。在40岁及以上人群中,PACG患病率男性为1.5%,女性为3.5%,总体人群为2.5%。患病率随年龄增长而增加。比较前房周边深度时,女性组前房明显比男性组窄(P<0.01)。有阳性家族史的受试者中PACG患病率显著高于有阴性家族史的受试者(P<0.02)。

结论

在长春双阳区农村地区,PACG患病率高于中国其他调查地区。性别、年龄、家族史和前房周边深度是PACG的重要危险因素。

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