Urruchi Fernández P, Cavero Rebollo O, Jiménez Mas J A, Martínez Bengoechea J, González Enguita C, Rioja Sanz L A
Servicio de Anatomía Patológica, Hospital Miguel Servet, Zaragoza, España.
Actas Urol Esp. 1991 Mar-Apr;15(2):205-8.
Appearance of residual masses following chemotherapy of retroperitoneal metastasis from testicle's non-seminomatous germinal cell tumour does not always imply we are facing an active tumoral disease. When exeresis of these masses discovers the presence of a mature teratoma during the histological study, what we have is the so called Growing Teratoma Syndrome. Such teratoma is unresponsive to chemotherapy but the patient can be cured by means of a full exeresis of the residual mass, thus the relevance of having into account the likelihood of this pathology. The paper presents the case of a patient with retroperitoneal non-seminomatous testicle tumour and metastasis which, following chemotherapy, presented a residual mass with normal serological markers. After the exeresis it was found out that it was made up by mature teratoma. Four months after rescue surgery, the patient remains asymptomatic, has normal markers and no signs of neoplastic recurrence.
睾丸非精原性生殖细胞肿瘤腹膜后转移化疗后残留肿块的出现并不总是意味着我们面对的是活动性肿瘤疾病。当对这些肿块进行切除并在组织学研究中发现存在成熟畸胎瘤时，我们所遇到的就是所谓的生长畸胎瘤综合征。这种畸胎瘤对化疗无反应，但通过对残留肿块进行完整切除，患者可以治愈，因此考虑这种病理情况的可能性具有重要意义。本文介绍了一例患有腹膜后非精原性睾丸肿瘤并伴有转移的患者，该患者化疗后出现血清学标志物正常的残留肿块。切除后发现其由成熟畸胎瘤组成。挽救性手术后四个月，患者仍无症状，标志物正常，无肿瘤复发迹象。
