Lauwers Patrick, Van den Broeck Sylvie, Carp Laurens, Hendriks Jeroen, Van Schil Paul, Blockx Pierre
Department of Thoracic and Vascular Surgery, University Hospital of Antwerp, Edegem, Belgium.
Angiology. 2007;58(6):717-24. doi: 10.1177/0003319707299205. Epub 2007 Dec 10.
Vascular graft infection is associated with a high morbidity and mortality rate. Diagnosis is difficult, as there is no single diagnostic criterion that has a 100% accuracy. A combination of physical examination, laboratory tests, and several imaging techniques is mandatory. Beside a wide range of indications in the oncological field, positron emission tomography with (18)F-fluorodeoxyglucose (FDG-PET) has a well-known role in the diagnosis of bone and soft-tissue infections. Some authors have recently reported on the potential use of FDG-PET in the diagnosis of vascular graft infections. The aim of this study is to review personal experience. Five consecutive patients with a suspected prosthetic infection (1 aortobifemoral bypass, 3 femoropopliteal bypasses, and 1 femorofemoral bypass) underwent FDG-PET. All prostheses showed a moderate or intense FDG tracer uptake. All 3 patients with an intense FDG uptake proved to have a prosthetic infection (based on microbiologic examination). These preliminary results suggest that FDG-PET might be an interesting tool to confirm vascular graft infection.
血管移植物感染与高发病率和死亡率相关。诊断困难，因为没有一种单一的诊断标准具有100%的准确性。体格检查、实验室检查和几种成像技术相结合是必不可少的。除了在肿瘤学领域有广泛的应用指征外，(18)F-氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)在骨和软组织感染的诊断中具有众所周知的作用。最近一些作者报道了FDG-PET在血管移植物感染诊断中的潜在应用。本研究的目的是回顾个人经验。连续5例疑似人工血管感染患者(1例主动脉双股动脉旁路移植术、3例股腘动脉旁路移植术和1例股股动脉旁路移植术)接受了FDG-PET检查。所有人工血管均显示出中度或强烈的FDG示踪剂摄取。FDG摄取强烈的3例患者均被证实存在人工血管感染(基于微生物学检查)。这些初步结果表明，FDG-PET可能是确诊血管移植物感染的一个有价值的工具。
