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[老年人认知功能减退知情者问卷(IQCODE)与认知测试表现之间的差异]

[Discrepancies between the IQCODE (Informant Questionnaire on Cognitive Decline in the Elderly) and cognitive test performance].

作者信息

Diesfeldt H F A

出版信息

Tijdschr Gerontol Geriatr. 2007 Oct;38(5):225-36.

Abstract

OBJECTIVES

The IQCODE is an informant-rated scale of estimated cognitive decline. This study examined the scalability of the 16-item form of the IQ-CODE and its validity to predict performance on a comprehensive cognitive battery.

METHODS

The medical files of 169 psychogeriatric day care attendants contained an IQCODE. Mokken's nonparametric item response model for polytomous items was used to assess the unidimensionality of the IQ-CODE. Tests of orientation, episodic memory and executive functioning (Behavioral Dyscontrol Scale, Category Fluency, and Expanded Mental Control Test) were administered in order to examine predictive validity.

RESULTS

Hi-coefficients of scalability for the 16 items of the IQCODE ranged from 0.33 to 0.50. Loevinger's H was 0.40 for he full scale, which makes it a moderately strong, unidimensional scale. A 'strong' scale (H = 0.54) was found by selecting a subset of seven items, representing the latent construct of problem solving ability. The correlations of the total IQCODE score with neuropsychological tests differed significantly from zero but the coefficients were quite small, ranging from -0.12 to -0.25. A nonparametric optimal discriminant analysis (ODA) was used to derive a cutoff score for the IQCODE that would maximize the classification accuracy in differentiating patients with comparatively high or low levels of cognitive functioning. Given an effect strength for sensitivity (ESS) of 21%, the optimal IQCODE cutoff score (3.75) did not reliably discriminate between different levels of cognitive ability. More than half of the patients (56%) who were predicted to belong to a group of low cognitive ability, in fact performed at a higher level. Conversely, overestimation of cognitive ability occurred less often (20%).

CONCLUSIONS

In this sample of psychogeriatric day care attendants the IQCODE tended to underestimate the patient's cognitive scores. In order to understand deficits or find remaining competencies, direct assessment of cognitive abilities may be preferred to informant based measures.

摘要

目的

IQCODE是一种由知情者评定的估计认知衰退程度的量表。本研究考察了16项版IQCODE的可扩展性及其预测综合认知测验表现的效度。

方法

169名老年精神科日间护理参与者的病历中包含IQCODE。采用莫肯多分类项目的非参数项目反应模型来评估IQCODE的单维性。进行了定向、情景记忆和执行功能测试(行为失控量表、类别流畅性和扩展心理控制测试)以检验预测效度。

结果

IQCODE的16个项目的高可扩展性系数范围为0.33至0.50。全量表的洛温杰H系数为0.40,这使其成为一个中等强度的单维量表。通过选择代表解决问题能力潜在结构的7个项目子集,发现了一个“强”量表(H = 0.54)。IQCODE总分与神经心理学测试的相关性显著不为零,但系数相当小,范围为-0.12至-0.25。采用非参数最优判别分析(ODA)得出IQCODE的临界分数,该分数将在区分认知功能水平相对较高或较低的患者时使分类准确性最大化。给定21%的敏感性效应强度(ESS),最优IQCODE临界分数(3.75)不能可靠地区分不同水平的认知能力。超过一半(56%)被预测属于低认知能力组的患者,实际上表现水平更高。相反,对认知能力的高估较少发生(20%)。

结论

在这个老年精神科日间护理参与者样本中,IQCODE往往低估患者的认知分数。为了了解缺陷或发现剩余能力,直接评估认知能力可能比基于知情者的测量更可取。

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