Meurer A, Lewens T, Schmitt D, Vetter T, Drees P
Orthopädische Klinik , Johannes-Gutenberg-Universität, Langenbeckstrasse 1, 55131 Mainz, Deutschland.
Orthopade. 2008 Jan;37(1):17-23. doi: 10.1007/s00132-007-1177-1.
Osteogenesis imperfecta (OI) is a congenital connective tissue disorder with an incidence of up to 1:30,000. Patients suffer from deformities and fractures, and many of them never reach ambulation. The therapy consists of conservative, medicamentous and operative procedures that are described in this article.
成骨不全症(OI)是一种先天性结缔组织疾病,发病率高达1:30000。患者会出现畸形和骨折,其中许多人终生无法行走。本文介绍了包括保守治疗、药物治疗和手术治疗在内的治疗方法。