Reiner G, Hepp S, Holweger K
Schweinekrankheiten, Justus-Liebig-Universität Giessen.
Dtsch Tierarztl Wochenschr. 2007 Nov;114(11):429-36.
Hematological traits are essential parameters for veterinary practice to quantify health status of individuals and herds. A major problem with the interpretation of hematological values is their pronounced variability that is to a great extend caused by non-systematic factors. Differences in breeds and populations are providing evidence for different genotypes in this regard, although there is no information available in swine about the nature and shares of participating genes. Goal of the present paper was to evaluate the additive-genetic share of total variability of traits of the red and white blood cell count. The results are based on 139 F2-pigs of a Pietrain-Meishan-family. Medium to high heritabilities have been estimated for the numbers of neutrophiles, the mean corpuscular hemoglobin concentration and the hemoglobin content, and for the shares of basophile granulocytes, platelets and lymphocytes. No meaningful shares of additive genetic variance were obvious in the other traits. Shares of additive genetic variance of the above mentioned traits argue for the existence of favourable and unfavourable gene variants to be involved in their phenotypic variation. Isolation of these variants might improve the diagnostical use of those traits in the future and provide a measure to advance general health in the pig.
血液学特征是兽医实践中量化个体和畜群健康状况的重要参数。血液学值解释的一个主要问题是其显著的变异性，这在很大程度上是由非系统性因素引起的。品种和群体的差异在这方面为不同的基因型提供了证据，尽管在猪中尚无关于参与基因的性质和份额的信息。本文的目的是评估红细胞和白细胞计数性状总变异性的加性遗传份额。结果基于皮特兰 - 梅山家系的139头F2代猪。已估计出嗜中性粒细胞数量、平均红细胞血红蛋白浓度和血红蛋白含量以及嗜碱性粒细胞、血小板和淋巴细胞份额的遗传力为中到高。在其他性状中未发现明显的加性遗传方差份额。上述性状的加性遗传方差份额表明存在有利和不利的基因变体参与其表型变异。分离这些变体可能会在未来改善这些性状在诊断中的应用，并为提高猪的总体健康状况提供一种手段。
